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TCS PrP Inhibitor 13

CAS No. 34320-83-7

TCS PrP Inhibitor 13 ( 5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One )

产品货号. M27727 CAS No. 34320-83-7

TCS PrP Inhibitor 13 is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥413 有现货
5MG ¥648 有现货
10MG ¥1037 有现货
25MG ¥2341 有现货
50MG ¥3686 有现货
100MG ¥5443 有现货
500MG ¥11583 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    TCS PrP Inhibitor 13
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    TCS PrP Inhibitor 13 is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.
  • 产品描述
    TCS PrP Inhibitor 13 is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.(In Vitro):In Schwannoma cells, administration of 0-500 μM TCS PrP Inhibitor 13 reduces levels of total ERK1/2, pAKT, total FAK, Cyclin D1, PrPC and increases expression of cleaved caspase-3 significantly. TCS PrP Inhibitor 13 also significantly reduces the number of proliferating, Ki67-positive cells and total cell number in Schwannoma cells.
  • 同义词
    5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    34320-83-7
  • 分子量
    281.3
  • 分子式
    C15H11N3O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    [O-][N+](=O)c1ccc(cc1)C1=NN(C(=O)C1)c1ccccc1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Ensslin HK, Kovar KA, Maurer HH. Toxicological detection of the designer drug 3,4-methylenedioxyethylamphetamine (MDE, "Eve") and its metabolites in urine by gas chromatography-mass spectrometry and fluorescence polarization immunoassay. J Chromatogr B Biomed Appl. 1996 Aug 30;683(2):189-97.
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